Polymyalgia Rheumatica (“PMR”) is an inflammatory disorder that primarily occurs in adults ages over the age of 65 that causes muscle pain and stiffness in the shoulders, upper arms, neck and hips, particularly in the morning or after periods of inactivity.  It is associated with giant cell arteritis, an inflammatory disorder of the blood vessels that causes symptoms of headache, visual problems, jaw pain and scalp tenderness.  PMR and giant cell arteritis can occur as co-morbid conditions.

The causes of PMR are unknown though genetic susceptibility involving the inheritance of specific genes, genetic mutations and environmental factor such as infections appear to be involved in the development of PMR.  Recurrence can occur.